Tirzepatide prices vary widely between South African sellers, and a flat price tells you very little when one presentation holds twice as much as another. This page lists every tirzepatide presentation we carry with the price per milligram worked out.
Tirzepatide Prices in South Africa
Pulled live from the shop, so this table cannot go stale.
| Presentation | Brand | Format | Size | Price | Per mg |
|---|---|---|---|---|---|
| Tirzepatide 60mg Self Mix | HD Labs | Self Mix Vial | 60mg | R2 080 | R34.67 |
| Tirzepatide 60mg Double Strength | Noventra Pharma | Pre-filled Pen | 60mg | R2 550 | R42.50 |
| Tirzepatide 60mg | Body Pharm | Pre-filled Pen | 60mg | R3 200 | R53.33 |
| T-Ret 30mg (15mg Retatrutide + 15mg Tirzepatide) | iPharma | Pre-filled Pen | 30mg | R1 880 | R125.33 |
| Tirzepsema 34mg | iPharma | Pre-filled Pen | 34mg | R2 500 | Blend |
| Tirsema 44 | HD Labs | Pre-filled Pen | 44mg | R2 180 | Blend |
How to Read That Table
The column that matters is per mg. The three straight tirzepatide presentations all hold 60mg, and the price gap between them is almost entirely format and brand: the self-mix vial is the cheapest per milligram, the pre-filled pens cost more because you are paying for the device.
T-Ret carries 15mg of tirzepatide alongside 15mg of retatrutide, so its per mg figure reflects the tirzepatide share only and is not a like-for-like comparison. Tirzepsema and Tirsema are marked as blends because we will not publish a per mg figure for a split we have not confirmed.
Pen or self mix vial
A pre-filled pen arrives ready, click-calibrated, no preparation. A self mix vial arrives as lyophilised powder with bacteriostatic water in the box. You reconstitute it yourself (our reconstitution guide walks through it), and our peptide calculator does the arithmetic. The vial is the value option. The pen is the easy one.
What Tirzepatide Is
Tirzepatide acts at two receptors: GLP-1 and GIP. GLP-1 signalling is associated with appetite, satiety and glucose handling. GIP is the second incretin hormone and is involved in nutrient metabolism and insulin signalling. Tirzepatide was the first compound to combine both in one molecule, which is why it is usually described as a dual agonist.
It sits between semaglutide, which acts at GLP-1 only, and retatrutide, which adds the glucagon receptor to the two tirzepatide already covers. The full comparison of all three goes further.
Tirzepatide is approved as a medicine under brand names in several countries. The presentations on this page are not those branded products. They are research compounds and are supplied for laboratory research use only.
Frequently Asked Questions
How much does tirzepatide cost in South Africa?
Across our range, a 60mg tirzepatide presentation costs between R2 080 and R3 200, which works out at roughly R35 to R53 per milligram. The HD Labs self-mix vial is the cheapest per milligram; pre-filled pens cost more.
Where can I buy tirzepatide in South Africa?
We supply tirzepatide as a research compound with flat R150 delivery anywhere in South Africa. Every presentation is listed in the table above with its price per milligram. It is supplied for laboratory research use only.
What is the difference between tirzepatide and semaglutide?
Semaglutide acts at one receptor, GLP-1. Tirzepatide acts at two, GLP-1 and GIP. Retatrutide acts at three, adding the glucagon receptor.
What is the difference between tirzepatide and retatrutide?
Retatrutide adds glucagon receptor activity to the GLP-1 and GIP activity tirzepatide already has. Tirzepatide is approved in several countries; retatrutide is still investigational everywhere. See our retatrutide price page.
How should tirzepatide be stored?
Refrigerated, out of direct light, never frozen once reconstituted. A sealed lyophilised vial tolerates room temperature in transit. Storage after delivery is the buyer’s responsibility.
Regulatory Status
The presentations on this page are research compounds, not registered medicines, and have not been evaluated by SAHPRA. They are supplied for laboratory research use only and are not for human or veterinary consumption. Nothing on this page is medical advice. Our write-up on peptide legality in South Africa covers the detail.
Ordering
Flat R150 delivery anywhere in South Africa. Browse the full weight loss and metabolic range, or contact us for help choosing between two presentations.